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Tango
Stout Shield
Iron BranchIron Branch
Quelling Blade
Boots of Speed
Ring of Basilius
Helm of Iron Will
Phase Boots
Armlet of Mordiggian
Battle Fury
Assault Cuirass
Black King Bar
Boots of Travel
Manta Style
Radiance
Mjollnir
Moon Shard
Monkey King Bar
Silver Edge
Heaven's Halberd
Heart of Tarrasque
Abyssal Blade
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2 | 5 | 7 | 12 |  |
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4 | 13 | 14 | 16 |  |
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1 | 3 | 8 | 9 |  |
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6 | 11 | 18 |  |
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10 | 15 |
Ancient Apparition
Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian (Inactive) Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Enchantress
Untouchable greatly reduces Chemical Rage's attack speed advantage.
Invoker
Quas-Exort, Exort Invoker can win the mid lane easily against Alchemist because Quas Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.
Lifestealer
Feast is good against high health and low armor Alchemist.
Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.
Necrophos
Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
Slardar
Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's low base armor, making it easy to quickly kill him with physical damage.
Slark
Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
Ursa
Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
Ember Spirit
Ember's magic damage build is able to burst down alchemist due to his low strength gain and alchemist normal item pick up.
Others
Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits.
Clinkz can take advantage of Alchemist's little armor to kill him.
Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.
Items
Assault Cuirass reduces Alchemist's already low base armor even further, and protects against his rapid physical attacks.
Shiva's Guard reduces Alchemist's attack speed and gives a fair amount of armor.
Heaven's Halberd is a troublesome item for many physical carries, as they are unable to hit anyone for some time, unless they can dispel it; Alchemist is no exception.
Scythe of Vyse disables Alchemist, making sure he won't be able to use his Chemical Rage to heal up, and allows heroes to burst him down fast.
Lotus Orb easily reflects Unstable Concoction, due to its long brewing time.
Broodmother
Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
Alchemist's Chemical Rage nullifies Broodmother's Insatiable Hunger.
Nature's Prophet
Acid Spray and Greevil's Greed will quickly destroy pushes with treants.
Phoenix
Chemical Rage kills Phoenix very quickly in Supernova.
Undying
Chemical Rage will take down Tombstone in no time.
Alchemist can also farm the zombies for easy Greevil's Greed gold.
Elder Titan
A well timed Echo Stomp will allow Alchemist to set up his Unstable Concoction safely without worry of self-stunning while looking for a target.
Tiny
Tiny is good early and mid-game oriented ganker, making more space for Alchemist. And he benefits a lot from Aghanim's Scepter, bestowed by Alchemist.
Oracle
False Promise and Fortune's End will purge debuffs away.
False Promise combined with Chemical Rage may give you some serious sustainability.
Fortune's End is an AoE purge, which will remove from enemies buffs like Guardian Guardian Angel and also root them.
Troll Warlord
Battle Trance combined with Chemical Rage makes Alchemist attack at insane speeds.
Others
Alchemist works well with any hero that benefits from Aghanim's, Aghanim's Scepter, as he can farm it for them (most likely far more quickly) and also free up an inventory slot.
Omniknight's Repel can cancel self stun from Unstable Concoction.
Entry
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